Case study: persistent recovery of hand movement and tactile sensation in peripheral nerve injury using targeted transcutaneous spinal cord stimulation

Peripheral nerve injury can lead to chronic pain, paralysis, and loss of sensation, severely affecting quality life. Spinal cord stimulation has been used in the clinic provide pain relief arising from peripheral injuries, however, its ability restore function after have not explored. Neuromodulation spinal through transcutaneous (tSCS), when paired with activity-based training, shown promising results towards restoring volitional limb control people injury. We show, for first time, effectiveness targeted tSCS strength (407% increase 1.79 ± 1.24 N up 7.3 0.93 N) significantly increasing hand dexterity an individual paralysis due a (PNI). Furthermore, this is study document persisting 3-point improvement during clinical assessment tactile sensation receiving 6 weeks tSCS. Lastly, motor sensory gains persisted several months was received, suggesting may long-lasting benefits, even PNI. Non-invasive shows tremendous promise as safe effective therapeutic approach broad applications functional recovery debilitating injuries.